Sickle Cell Pain Crisis: Clinical Guidelines for the Use of Oxygen

Abstract:


Nocturnal hypoxemia is a prelude to vaso‐occlusive crisis (VOC). Vascular occlusion and disruption of tissue oxygenation are a prequel to excruciating pain, chest splinting with further hypoxemia, acute chest syndrome, hemolysis, distal tissue ischemia, ischemia-reperfusion injury, concomitant inflammation, resulting in organ damage and other complications with increased morbidity and mortality. Oxygen therapy is a simple yet cost-effective way to prevent VOC and its attendant morbidity and mortality.

Related Articles

A New Minimally Invasive Procedure for Muscle, Back,
Neck Pain and Radiculopathy – The Myofascial Nerve
Block

This is the first description of a procedure targeting the myofascial tissues since Janet Travell’s
description of myofascial trigger points in 1942. However unlike trigger point injections, this
minimally invasive myofascial nerve injection is performed differently and targets the myofascial
tissues, peripheral innervations, posterior spinal structures and spinal nerve roots at the same
time. It is different from a trigger point injection that aims to block trigger points within a muscle.
Prolonged standing or sitting, posture and other multiple factors can create recurrent injuries
with attendant inflammation and episodically aggravate pain. Thus there is a need for a simple
intervention technique that can be performed from the medical clinic to the battlefield to quickly
relieve inflammation and prevent chronic pain.

Responses